Calcium efflux fromMyxicolagiant axons: effects of extracellular calcium and intracellular EGTA
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چکیده
منابع مشابه
Calcium Efflux from Internally Dialyzed Squid Giant Axons
Calcium efflux has been studied in squid giant axons under conditions in which the internal composition was controlled by means of a dialysis perfusion technique. The mean calcium efflux from axons dialyzed with 0.3 microM calcium and 5 mM ATP was 0.26 pmol/cm(2).s at 22 degrees C. The curve relating the Ca efflux with the internal Ca concentration had a slope of about one for [Ca](i) lower tha...
متن کاملCalcium efflux from squid axons under constant sodium electrochemical gradient
The effect of varying Nao and Nai on Ca efflux while maintaining the ratio Nao/Nai constant was explored in squid giant axons dialyzed with and without ATP. In the absence of ATP, the Ca efflux increased 3.4 +/- 0.2-fold when the Nao/Nai concentrations were reduced from 440/80 to 110/20 mM. In the presence of ATP a similar change did not have an appreciable effect. The inhibition of Ca efflux p...
متن کاملA Study on the Effects of Modulation of Intracellular Calcium on Excisional Wound Healing in Rabbit
An in vitro study on the role of intracellular calcium ions in healing of excisional wound in rabbit was undertaken. We employed two drugs namely, glibenclamide and nitroglycerin that are topically applied in vivo to modulate the activity of intracellular calcium. Our model consisted of a 15 ´ 15 mm excisional wound. Seven groups of New Zealand rabbits were used. The first three groups served a...
متن کاملExtracellular calcium sensing and extracellular calcium signaling.
The cloning of a G protein-coupled extracellular Ca(2+) (Ca(o)(2+))-sensing receptor (CaR) has elucidated the molecular basis for many of the previously recognized effects of Ca(o)(2+) on tissues that maintain systemic Ca(o)(2+) homeostasis, especially parathyroid chief cells and several cells in the kidney. The availability of the cloned CaR enabled the development of DNA and antibody probes f...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1980
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1980.sp013390